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Visible-Light-Driven Decarboxylative Coupling of 2H-Indazoles with α-Keto Acids without Photocatalysts and Oxidants

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journal contribution
posted on 2024-06-10, 11:03 authored by Mengyu Niu, Chen Yang, Mingzhu Leng, Qun Cao, Meichao Li, Zhenlu Shen
An efficient synthesis of functionalized 3-acyl-2H-indazoles via visible-light-induced self-catalyzed energy transfer was developed. This method utilized a self-catalyzed energy transfer process between 2H-indazoles and α-keto acids, offering advantages like absence of photosensitizers, metal catalysts, and strong oxidants, broad substrate compatibility, and operational simplicity under mild conditions.

History

Author affiliation

College of Science & Engineering Chemistry

Version

  • VoR (Version of Record)

Published in

The Journal of Organic Chemistry

Volume

89

Issue

9

Pagination

6159 - 6168

Publisher

American Chemical Society (ACS)

issn

0022-3263

eissn

1520-6904

Copyright date

2024

Available date

2024-06-10

Spatial coverage

United States

Language

en

Deposited by

Mr Qun Cao

Deposit date

2024-05-28

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