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Y-chromosome descent clusters and male differential reproductive success: Young lineage expansions dominate Asian pastoral nomadic populations

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posted on 2015-01-16, 15:51 authored by Patricia Balaresque, Nicolas Poulet, Sylvain Cussat-Blanc, Patrice Gerard, Lluis Quintana-Murci, Evelyne Heyer, Mark A. Jobling
High-frequency microsatellite haplotypes of the male-specific Y-chromosome can signal past episodes of high reproductive success of particular men and their patrilineal descendants. Previously, two examples of such successful Y-lineages have been described in Asia, both associated with Altaic-speaking pastoral nomadic societies, and putatively linked to dynasties descending, respectively, from Genghis Khan and Giocangga. Here we surveyed a total of 5321 Y-chromosomes from 127 Asian populations, including novel Y-SNP and microsatellite data on 461 Central Asian males, to ask whether additional lineage expansions could be identified. Based on the most frequent eight-microsatellite haplotypes, we objectively defined 11 descent clusters (DCs), each within a specific haplogroup, that represent likely past instances of high male reproductive success, including the two previously identified cases. Analysis of the geographical patterns and ages of these DCs and their associated cultural characteristics showed that the most successful lineages are found both among sedentary agriculturalists and pastoral nomads, and expanded between 2100 BCE and 1100 CE. However, those with recent origins in the historical period are almost exclusively found in Altaic-speaking pastoral nomadic populations, which may reflect a shift in political organisation in pastoralist economies and a greater ease of transmission of Y-chromosomes through time and space facilitated by the use of horses.

History

Citation

European Journal of Human Genetics, 2015, doi: 10.1038/ejhg.2014.285

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Biological Sciences/Department of Genetics

Version

  • AM (Accepted Manuscript)

Published in

European Journal of Human Genetics

Publisher

Nature Publishing Group for European Society of Human Genetics

issn

1018-4813

eissn

1476-5438

Copyright date

2015

Available date

2015-07-14

Publisher version

http://www.nature.com/ejhg/journal/vaop/ncurrent/full/ejhg2014285a.html

Notes

The file associated with this record is embargoed until 6 months after the date of publication. The final published version may be available through the links above.

Language

en

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